Véron L, Bessa R, Boisnard A, Cavadias I, Chabut M, Desmedt C, Loiseau C, Parmentier A, Quarez L, Sylvestre C, Rousset-Jablonski C
Bull Cancer . 2026 May 19:S0007-4551(26)00226-2
doi: 10.1016/j.bulcan.2026.03.009
PMID: 42156259
ABSTRACT
Gynecological follow-up of women who have undergone hematopoietic stem cell transplantation (HSCT) is complex, as it has multiple issues: fertility preservation; management of premature ovarian insufficiency or early menopause; infectious risk, particularly related to human papillomavirus; hemorrhagic risk during aplasia; screening for specific complications such as graft-versus-host disease (GVHD, only in the setting of allogeneic transplantation) or radiation-induced breast cancer; sexual and emotional health, etc. Clinical practices vary widely and remain heterogeneous among hospitals. The aim of this article is to provide a synthesis of the main gynecological issues and to propose French clinical practice recommendations in order to harmonize, systematize, and structure the gynecological follow-up of women undergoing HSCT.
Keywords: Femmes; Greffe de cellules souches hématopoïétiques; Gynecological follow-up; Hematopoietic cell stem transplantation; Suivi gynécologique.
